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FILE In this Oct. 14, 2016 photo, an Amtrak Acela train travels along wholesale nfl jerseys the shore where people are fishing in Old Saybrook, Conn. cheap nfl jerseys authentic The federal government is rethinking the construction of new high speed railroad tracks through parts of Connecticut and Rhode Island after complaints that the
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project would devastate neighborhoods, marshlands and tourist attractions. (AP Photo/Michael Dwyer, File)
Conclusions: While 3 phase 3 investigations of armodafinil as adjunctive treatment for bipolar I depression yielded varying efficacy results (only 1 with statistical significance vs placebo; 2 with a non significant numerical advantage vs placebo), a pooled analysis of these 3 similarly designed studies demonstrated that adjunctive armodafinil 150 mg provided a statistically significant improvement in major depressive episode symptoms associated with bipolar I disorder as measured by the mean change in IDS C30 at week 8 (primary efficacy parameter). This finding was further supported by several secondary efficacy outcomes. Adjunctive armodafinil was generally well tolerated across all 3 studies, with nearly equal percentages of patients discontinuing due to AEs with adjunctive armodafinil vs adjunctive placebo. Amchin and R. Yang are employees of Teva Pharmaceuticals. T. Ketter and M. Frye are consultants for Teva Pharmaceuticals. This study was sponsored by Teva Pharmaceuticals. Medical writing support was provided by John H. Simmons, MD, at Peloton Advantage, LLC, and was funded by Teva Pharmaceuticals.